I know this is an old thread, but I am also having problems with sequential signing. We are trying to validate a workflow with Acrobat for internal use, and then use EchoSign for 21CFR compliant signatures. I have valdiated the process through EchoSign, but there are a few problems.
1. Using an internal signature process, I apply a Signature with Certificate and everything I know of configured correctly. When the second person receives the file by e-mail, or opens from the network location and attempts to sign they are receiving a "file is read only" error, so the file must be save as under a new name?
2. The workflow I would like to have is send the document for signature with the restrictions applied under the Certifying dialog. But then once it is signed my QAU wants to apply a final security to prevent anyone from being able to print out the final doc. The security cannot be changed because the file is signed.
3. If we have a finalized document internal with signatures, when it is sent through EchoSign the signature fields are removed and EchoSign takes precedence (so it destroys the original document properties).