Yes it is possible in muse. Simply you have to play with opacity in the scrolling effects panel.Mae your first image invisible when you scroll down.
Firstly you have to place your image and then use the scroll bar effects, make it stuck on the header panel, set its opacity to 0% at initial position and 100% at final. Its not that complicated as I tried to explain it
If still having trouble, than look for tutorials on adobe tv, regarding scrolling effects & opacity..
Cheers..!